| Distance | Event | School | Name | Year | Time |
| 200 | Medley Relay | Wisconsin | Grulke, Gibbs, Woodard, Anderson | 1989 | 2:28.50 |
| 200 | Freestyle | Iowa | Grace Johanns | 2017 | 2:26.06 |
| 200 | Individual Medley | Iowa | Grace Johanns | 2016 | 2:42.49 |
| 50 | Freestyle | Iowa | Grace Johanns | 2018 | 27.57 |
| 100 | Butterfly | Wisconsin | Grace Johanns | 2018 | 1:16.28 |
| 100 | Freestyle | Iowa | Grace Johanns | 2017 | 1:04.29 |
| 500* | Freestyle | Iowa | Grace Johanns | 2016 | 6:28.53 |
| 200 | Freestyle Relay | Kentucky | Spencer, Dunham, Courts, Wilkerson | 2002 | 2:24.59 |
| 200 | Freestyle Co-Ed Relay | Iowa | Johanns, Hughes, Berglund, Gillaspie | 2013 | 2:52.03 |
| 100 | Backstroke | Iowa | Grace Johanns | 2017 | 1:20.29 |
| 100 | Breaststroke | Tennessee | Missy Akins | 1980 | 1:23.10 |
| 400 | Freestyle Relay | Wisconsin | Rezutek, Marx, Smith, Woodard | 1989 | 5:04.07 |
| 400 | Freestyle Co-ed Relay | Indiana | Steiner, Nicola, Baugh, Oklak | 2004 | 5:24.35 |
| 200 | Freestyle Co-ed Relay | Iowa | Berglund, Hughes, Sheridan, Morgan | 2012 | 2:42.38 |
* 400 Yard Freestyle was replaced by the 500 Yard Freestyle
*400 Yard Freestyle Co-Ed was replaced with the 200 Yard Freestyle Co-Ed